A new comic starring Superman, Mr. Mxyzptlk, and Calendar Man shows how Gwenpool would put up a good fight against the Man of Steel.
Warning! Spoilers for Batman/Superman #22 by DC Comics below
In a new adventure starring fifth-dimensional imp, Mister Mxyzptlk, the villain proved that by giving Calendar Man comic awareness, he was able to hurt Superman by breaking the Fourth Wall. In Batman/Superman #22, Calendar Man reaches across a panel to hit Superman with his own ice breath. The moment shows that the Marvel Comics hero Gwenpool would also be able to pull the same trick on Superman.
Some characters in comics have comic awareness, meaning they know they’re in a comic and can manipulate the stories they star in. Among heroes who have gained the abilities to break the Fourth Wall, include She-Hulk, Deadpool, Howard the Duck, and Gwenpool. However, Gwenpool has taken the Fourth Wall breaking to a new level, as her solo adventures have featured her jumping from comic to comic, with full awareness that she was in a story the entire time. She’s jumped across and moved panels, interacted with design details, and manipulated things to her favor.